Cationic drug: pharmaceutical industry: Modified-release dosage forms: For example, a cationic, or positively charged, drug can be bound to an anionic. The inhibitory effects of cationic drugs (beta-adrenoreceptor antagonists, calcium (Ca)-channel blocker, I(f) channel inhibitor, antiarrhythmic drugs, and. In addition, many diabetes educators are confused by drug interaction terminology . Metformin and cimetidine, both cationic (positively charged) drugs , can.
Cation exchange resins are used in medicine to remove an excess of a particular positively charged ion that has accumulated in the body. When the resin is. The purpose of this study was to clarify the competition and the mechanism of intestinal absorption of various cationic drugs by in situ and in vitro techniques. The lipophilicity of cationic drugs can be increased by forming ion pairs with the carboxylate anion of fatty acids. Transport of cations across an isopropyl.
The overall goals of this paper are (i) to understand the binding mechanism between two cationic drugs (namely procaine hydrochloride (PrHy) and imipramine. Cationic amphiphilic drugs (CADs) comprise a wide variety of different substance classes such as antidepressants, antipsychotics, and. How a drug distributes within highly compartmentalized mammalian cells can affect both the activity and pharmacokinetic behavior. By LLOYD KENNONt and TAKERU HIGUCHI. A study of the interaction of sodium carboxymethylcellulose with a number of cationic drugs indicated that even.